BDBM50618897 CHEMBL5394880
SMILES COc1cc(cc2CCN(CC(F)(F)F)C(=O)c12)-c1cnc(Nc2cc(nc(C)n2)N2CCN(C)CC2)s1
InChI Key InChIKey=WCLYSPWUHSZWOR-UHFFFAOYSA-N
Data 10 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 50618897
Affinity DataIC50: 0.600nMAssay Description:Inhibition of SIK2 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 0.700nMAssay Description:Inhibition of SIK2 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 5.90nMAssay Description:Inhibition of SIK3 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 17nMAssay Description:Inhibition of SIK3 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of SIK1 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of SIK1 (unknown origin) using AMARA as substrate buffer incubated for 60 mins followed by addition of ADP-Glo reagent further incubated f...More data for this Ligand-Target Pair
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of human CYP2C19 by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP3A4 using midazolam as substrate by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP2C9 by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human CYP1A2 by LC-MS/MS analysisMore data for this Ligand-Target Pair
