BDBM50619175 CHEMBL5418532

SMILES Cc1cccc(c1)C1OC(Nc2nc(N)nc(n2)N2CCOCC2)=NC(=C1)c1ccccc1

InChI Key InChIKey=XLKMKHQSIJADFX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619175   

TargetDipeptidyl peptidase 4(Human)
Sam Higginbottom University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50619175(CHEMBL5418532)
Affinity DataIC50: 78nMAssay Description:Inhibition of human recombinant DPP-4 using H-GlyPro-AMC as substrate incubated for 10 mins by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 8(Human)
Sam Higginbottom University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50619175(CHEMBL5418532)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal GST/His-tagged human recombinant DPP-8 (1 to 898 residues) expressed in Sf9 insect cells using Ala-Pro-AMC dipeptide as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetDipeptidyl peptidase 9(Human)
Sam Higginbottom University of Agriculture

Curated by ChEMBL
LigandPNGBDBM50619175(CHEMBL5418532)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant DPP-9 short form (1 to 863 residues) expressed in Sf9 cells using Ala-Pro-AMC dipeptide as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed