BDBM50619201 CHEMBL4750140

SMILES Oc1ccc(cc1)N1CCN(CC1)C(=O)CN1CCC(Cc2ccccc2)CC1

InChI Key InChIKey=YQAQFFRPWGNWEQ-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50619201   

TargetSigma non-opioid intracellular receptor 1(Rat)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50619201(CHEMBL4750140)
Affinity DataKi:  24nMAssay Description:Displacement of [3H](+)-pentazocine from rat liver homogenates sigma 1 receptor assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50619201(CHEMBL4750140)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [H3]DTG from rat liver homogenates sigma 2 receptor assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetPolyphenol oxidase 4(Agaricus bisporus)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50619201(CHEMBL4750140)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of mushroom tyrosinase using L-DOPA as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetTyrosinase(Human)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50619201(CHEMBL4750140)
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of human tyrosinase using L-DOPA as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed