BDBM50619337 CHEMBL5406998

SMILES Cc1n[nH]c2N[C@@H]([C@H]([C@H](O)c12)n1nnc2ccccc12)c1ccccc1

InChI Key InChIKey=OPZLYEPKPOCRPI-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619337   

TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619337(CHEMBL5406998)
Affinity DataEC50:  1.10E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619337(CHEMBL5406998)
Affinity DataEC50:  1.40E+3nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619337(CHEMBL5406998)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed