BDBM50619341 CHEMBL5440774

SMILES Cc1n[nH]c2c1[C@@H](O)[C@H](n1nnc3ccccc31)[C@@H](c1ccccc1F)N2

InChI Key InChIKey=CGOMAGNHDVQWRL-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50619341   

TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619341BDBM50619341(CHEMBL5440774)
Affinity DataEC50:  970nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619341BDBM50619341(CHEMBL5440774)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed