BDBM50619354 CHEMBL5408859

SMILES Cc1n[nH]c2N[C@H](C3CCCCC3)[C@H]([C@H](O)c12)n1nnc2ccccc12

InChI Key InChIKey=OLIATESFKHNVTC-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50619354   

TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619354(CHEMBL5408859)
Affinity DataEC50:  370nMAssay Description:Chaperone activity at GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetLysosomal acid glucosylceramidase(Human)
Eisai

Curated by ChEMBL
LigandPNGBDBM50619354(CHEMBL5408859)
Affinity DataIC50: 650nMAssay Description:Inhibition of GCase N370S GBA mutant in patient derived fibroblast cells using 4-methylumbelliferyl-beta-D-glucopyranoside as substrate incubated for...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed