BDBM50619373 CHEMBL5420469

SMILES C=CC(=O)N1CCC[C@@H](n2nc(-c3ccc(NC(=O)C45CC6CC(CC(C6)C4)C5)c4c3OCO4)c3c(N)ncnc32)C1

InChI Key InChIKey=KKAJAZGYTYTJBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50619373   

TargetTyrosine-protein kinase BTK(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619373BDBM50619373(CHEMBL5420469)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of BTK (unknown origin) preincubated for 10 mins followed by kinase substrate and ATP addition and measured for 20 mins by mobility shift ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619373BDBM50619373(CHEMBL5420469)
Affinity DataIC50: 500nMAssay Description:Inhibition of JAK3 (unknown origin) preincubated for 10 mins followed by kinase substrate and ATP addition and measured for 30 mins by mobility shift...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed