BDBM50619501 4-(4-hydroxybenzylidene) curcumin::CHEMBL260079

SMILES COc1cc(/C=C/C(=O)C(=Cc2ccc(O)cc2)C(=O)/C=C/c2ccc(O)c(OC)c2)ccc1O

InChI Key InChIKey=PVPLSZWXTGWUKB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50619501   

TargetAlpha-synuclein(Human)
Zhengzhou University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50619501BDBM50619501(CHEMBL260079 | 4-(4-hydroxybenzylidene) curcumin)
Affinity DataIC50: 4.39E+3nMAssay Description:Inhibition of alpha-Synuclein (unknown origin) aggregation incubated for 72 hrs by ThT-based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed