BDBM50619636 CHEMBL5402781

SMILES Cc1c(c(c(o1)C)S(=O)(=O)N)C(=O)O

InChI Key InChIKey=YPWRJNLSEWKOGW-UHFFFAOYSA-N

Data  2 KI  1 IC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50619636   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
University Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50619636(CHEMBL5402781)
Affinity DataKi:  9.81E+3nMAssay Description:Binding affinity to bacterial NDM-1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
University Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50619636(CHEMBL5402781)
Affinity DataKi:  9.82E+3nMAssay Description:Binding affinity to NDM1 (unknown origin) expressed in Escherichia coli BL21 (DE3) assessed as inhibition constant using IPM as substrate incubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetAngiotensin-converting enzyme(Human)
University Sains Malaysia

Curated by ChEMBL
LigandPNGBDBM50619636(CHEMBL5402781)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of angiotensin-converting enzyme (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed