BDBM50619956 CHEMBL5418170
SMILES CCn1nc(C)cc1C(=O)Nc1nc2cc(cc(OC)c2n1NCCCC(=O)NCc1ccc(F)cc1)C(N)=O
InChI Key InChIKey=WQRPONOBJRBTQQ-UHFFFAOYSA-N
Data 9 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50619956
Affinity DataEC50: 30nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in IL-6 level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
Affinity DataEC50: 120nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in CXCL10 level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
Affinity DataEC50: 270nMAssay Description:Activation of STING signalling pathway in human PBMC cells assessed as increase in IFN-beta level incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+3nMAssay Description:Agonist activity at STING in human THP1-Dual cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Activation of STING signalling pathway in human THP1-Dual cells assessed as increase in IRF-luciferase activation incubated for 24 hrs by QUANTI-luc ...More data for this Ligand-Target Pair
Affinity DataEC50: 4.74E+3nMAssay Description:Activation of STING signalling pathway in human wild type THP-1 cells assessed as increase in IFN-beta secretion incubated for 4 hrs by ELISA methodMore data for this Ligand-Target Pair
Affinity DataEC50: 5.50E+3nMAssay Description:Activation of STING signalling pathway in human THP1-Dual cells assessed as increase in NF-kappaB-SEAP activation incubated for 24 hrs by QUANTI-Blue...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in mouse RAW-Lucia ISG cells by luciferase gene reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at STING in human STHP1-Dual KO-STING cells incubated for 20 hrs by Quanti-luc reagent based assayMore data for this Ligand-Target Pair