BDBM50620492 CHEMBL5417514

SMILES [H][C@]12CN(CCN1Cc1cc(C#CC)c(c(F)c1OC2)-c1c(O)cccc1Cl)C(=O)C=C

InChI Key InChIKey=CNQOLVBNICGIJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50620492   

TargetGTPase KRas(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50620492(CHEMBL5417514)
Affinity DataIC50: 15nMAssay Description:Inhibition of biotinylated Avi-His tagged GDP-bound human KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli assessed as inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed