BDBM50620494 CHEMBL5431650

SMILES [H][C@@]12CN(CCN1Cc1ccc(c(Cl)c1OC2)-c1c(C)ccc2[nH]ncc12)C(=O)C=C

InChI Key InChIKey=HKCSRGQGNGOUGG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50620494   

TargetGTPase KRas(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50620494(CHEMBL5431650)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of biotinylated Avi-His tagged GDP-bound human KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli assessed as inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed