BDBM50620513 CHEMBL5436936

SMILES Oc1cccc(Cl)c1-c1c(F)cc(CN2CCN(CC2)C(=O)C=C)cc1C#C

InChI Key InChIKey=LRJRLUOCKAVWJI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50620513   

TargetGTPase KRas(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50620513(CHEMBL5436936)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of biotinylated Avi-His tagged GDP-bound human KRAS G12C mutant (1 to 166 residues) expressed in Escherichia coli assessed as inhibition o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed