BDBM50620757 CHEMBL5426124

SMILES Oc1cc2nc(-c3ccccc3)n(-c3ccccc3)c(=O)c2c(O)c1O

InChI Key InChIKey=PNPMYLKONYDRLR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50620757   

TargetReplicase polyprotein 1ab(2019-nCoV)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620757(CHEMBL5426124)
Affinity DataIC50: 83nMAssay Description:Inhibition of SARS-CoV-2 Main protease expressed in Escherichia coli BL21 (DE3) using fluorogenic peptide Dabcyl-KLSAVLQSGFRKM-Edans-NH2 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProthrombin(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620757(CHEMBL5426124)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Thrombin using fluorogenic substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCathepsin B(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620757(CHEMBL5426124)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Cathepsin B using fluorogenic substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCaspase-2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620757(CHEMBL5426124)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Caspase 2 using fluorogenic substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetProcathepsin L(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620757(CHEMBL5426124)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Cathepsin L using fluorogenic substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetCathepsin D(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50620757(CHEMBL5426124)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human Cathepsin D using fluorogenic substrate by FRET-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed