BDBM50620779 CHEMBL5435112

SMILES OC(=O)Cn1nc(Cc2ccccc2Cl)oc1=O

InChI Key InChIKey=CVIMYIWEZWQKEC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50620779   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50620779(CHEMBL5435112)
Affinity DataIC50: 1.85E+3nMAssay Description:Inhibition of NLRP3-dependent pyroptosis in PMA-differentiated human THP-1 cells assessed as inhibition of LPS/ATP-induced cell death pretreated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Human)
University of Turin

Curated by ChEMBL
LigandPNGBDBM50620779(CHEMBL5435112)
Affinity DataIC50: 3.26E+4nMAssay Description:Inhibition of NLRP3 inflammasome activation in PMA-differentiated human THP-1 cells assessed as inhibition of LPS/ATP-induced IL-1 beta release pretr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed