BDBM50620781 CHEMBL5438526

SMILES CC1(CNc2ncc(-c3ccncc3)c(n2)-c2cccs2)CCOC1

InChI Key InChIKey=ICJLXOLQDZZOEN-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50620781   

TargetAdenosine receptor A1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50620781(CHEMBL5438526)
Affinity DataKi:  2nMAssay Description:Antagonist activity at human A1R expressed in Flp-In-CHO cells assessed as NECA-mediated reduction in forskolin-stimulated cAMP accumulation by measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetAdenosine receptor A1(Human)
Uppsala University

Curated by ChEMBL
LigandPNGBDBM50620781(CHEMBL5438526)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]DPCPX from human A1R expressed in Flp-In-CHO cells incubated for 12 hrs by microbeta plate counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed