BDBM50621123 CHEMBL5413467

SMILES NS(=O)(=O)Oc1ccc2c(C(=O)c3ccc(OCCN4CCCCC4)cc3)c(sc2c1)-c1ccc(O)cc1

InChI Key InChIKey=CVTNCEDRLOXCLH-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621123   

TargetEstrogen receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50621123(CHEMBL5413467)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]estradiol from human ER-alpha expressed in Sf21 cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetEstrogen receptor(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50621123(CHEMBL5413467)
Affinity DataIC50: 5.20nMAssay Description:Displacement of [3H]estradiol from human ER-alpha expressed in Sf21 cells incubated for 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50621123(CHEMBL5413467)
Affinity DataIC50: 332nMAssay Description:Inhibition of STS in human JEG-3 cells assessed as inhibition of estrone E1 formation using [3H]estrone sulfate as substrate incubated for 20 hrs in ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSteryl-sulfatase(Human)
University of Sharjah

Curated by ChEMBL
LigandPNGBDBM50621123(CHEMBL5413467)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of STS in human JEG-3 cell lysates assessed as inhibition of estrone E1 formation using [3H]estrone sulfate as substrate incubated for 1 h...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed