BDBM50621259 CHEMBL5396697

SMILES CS(=O)(=O)NC(=O)c1cc(N2CCC(CC2)N2CCOCC2)c2c(nn(-c3ccccc3)c2n1)C1CCC1

InChI Key InChIKey=XYBQSRRFUUGKSB-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621259   

LigandPNGBDBM50621259(CHEMBL5396697)
Affinity DataEC50:  39nMAssay Description:Corrector activity at CFTR F508del mutant in forskolin-stimulated human bronchial epithelial cells derived from primary CF assessed as increase in me...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
LigandPNGBDBM50621259(CHEMBL5396697)
Affinity DataEC50:  119nMAssay Description:Corrector activity at CFTR F508del mutant in forskolin-stimulated human bronchial epithelial cells derived from primary CF assessed as GLPG1837-media...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
LigandPNGBDBM50621259(CHEMBL5396697)
Affinity DataEC50:  147nMAssay Description:Corrector activity at HRP-tagged CFTR F508del mutant in human CFBE41o- cells assessed as rescue trafficking by measuring increase in membrane express...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
LigandPNGBDBM50621259(CHEMBL5396697)
Affinity DataEC50:  502nMAssay Description:Corrector activity at HRP-tagged CFTR F508del mutant in human CFBE41o- cells assessed as rescue trafficking by measuring increase in membrane express...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed