BDBM50621288 CHEMBL5412411

SMILES COc1cc(cc2CCN(C3CC3)C(=O)c12)-c1cnc2cc(OCCN3CCOCC3)ccn12

InChI Key InChIKey=NCQKIKYQHVNIMN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621288   

TargetSerine/threonine-protein kinase SIK3(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50621288(CHEMBL5412411)
Affinity DataIC50: 12nMAssay Description:Inhibition of full length SIK3 (unknown origin) using AMARA peptide as substrate incubated for 120 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK2(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50621288(CHEMBL5412411)
Affinity DataIC50: 52nMAssay Description:Inhibition of full length human SIK2 using AMARA peptide as substrate incubated for 120 mins in presence of ATP by ADP-Glo kinase assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase SIK1(Human)
Galapagos

Curated by ChEMBL
LigandPNGBDBM50621288(CHEMBL5412411)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of N-terminal GST-tagged wild type human SIK1 (1 to 783 residues) expressed in baculovirus-infected Sf21 cells using AMARA peptide as subs...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed