BDBM50621298 CHEMBL5414831

SMILES OB(O)C(NC(=O)c1cnn(Cc2ccccc2)c1)c1cccc(Cl)c1

InChI Key InChIKey=ZXWADSDWEAQLAR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621298   

TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621298(CHEMBL5414831)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 60 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621298(CHEMBL5414831)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human FXIIa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 5 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCoagulation factor XII(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621298(CHEMBL5414831)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human FXIIa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 60 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621298(CHEMBL5414831)
Affinity DataIC50: 4.00E+5nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 5 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed