BDBM50621301 CHEMBL5405101

SMILES Cc1ccc(C(NC(=O)c2cnn(Cc3ccc(Cn4ccccc4=O)cc3)c2)B2OC(C)(C)C(C)(C)O2)c(F)c1

InChI Key InChIKey=AFMXDJSYGSJSDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621301   

TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621301(CHEMBL5405101)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 60 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621301(CHEMBL5405101)
Affinity DataIC50: 17nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 10 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlasma kallikrein(Human)
University of Nottingham

Curated by ChEMBL
LigandPNGBDBM50621301(CHEMBL5405101)
Affinity DataIC50: 94nMAssay Description:Inhibition of human PKa using H-D-Pro-Phe-Arg-AFC peptide substrate measured after 1 mins by fluorometric assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed