BDBM50621394 CHEMBL5438548

SMILES C[C@H](NC(=O)[C@@H]1C[C@@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCCCCNCc1cc(C)c(-c2ncn(C)c2-c2ccnc3cc(F)ccc23)c(C)c1)C(C)(C)C)c1ccc(cc1)-c1scnc1C

InChI Key InChIKey=BOTJARXURVIORK-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50621394   

TargetHistone-lysine N-methyltransferase NSD3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621394(CHEMBL5438548)
Affinity DataEC50:  940nMAssay Description:Induction of NSD3 degradation in human A549 cells measured after 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase NSD3(Human)
Shanghai Institute of Materia Medica

Curated by ChEMBL
LigandPNGBDBM50621394(CHEMBL5438548)
Affinity DataEC50:  1.43E+3nMAssay Description:Induction of NSD3 degradation in human NCI-H1703 cells incubated for 72 hrs by Western blot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed