BDBM50621413 CHEMBL5409449

SMILES CCN1CCN(CCCOc2cc3nccc(Oc4c(F)cc(NC(=O)NN5C(SCC5=O)c5ccc(F)cc5F)cc4F)c3cc2OC)CC1

InChI Key InChIKey=CTSDMCNSBRVZGJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50621413   

TargetMacrophage-stimulating protein receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of RON (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHepatocyte growth factor receptor(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 4.30nMAssay Description:Inhibition of c-MET (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTyrosine-protein kinase receptor UFO(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 27nMAssay Description:Inhibition of AXL (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase receptor Ret(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 28nMAssay Description:Inhibition of RET (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 110nMAssay Description:Inhibition of PDGFRbeta (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 145nMAssay Description:Inhibition of ABL (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50621413(CHEMBL5409449)
Affinity DataIC50: 362nMAssay Description:Inhibition of FLT3 (unknown origin) by kinome scan assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed