BDBM50621640 CHEMBL5406071

SMILES COc1cc2nc(nc(NCc3c(C)cc(C)[nH]c3=O)c2cc1OC)N1CCCN(C)CC1

InChI Key InChIKey=KBLFJYYDDWJDKG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621640   

TargetHistone-lysine N-methyltransferase EHMT2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621640BDBM50621640(CHEMBL5406071)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant EHMT2 G9a using SAM as substrate incubated for 1 hr by microplate luminescence based HMT assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EHMT2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621640BDBM50621640(CHEMBL5406071)
Affinity DataIC50: 15nMAssay Description:Inhibition of G9a (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621640BDBM50621640(CHEMBL5406071)
Affinity DataIC50: 53nMAssay Description:Inhibition of human EZH2 using SAM as substrate incubated for 1 hr by microplate luminescence based HMT assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase EZH2(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621640BDBM50621640(CHEMBL5406071)
Affinity DataIC50: 53nMAssay Description:Inhibition of EZH2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed