BDBM50621653 CHEMBL5396279

SMILES Cc1cc(cnc1-c1ccnc2ccccc12)-c1ccc(s1)S(N)(=O)=O

InChI Key InChIKey=OPDJFQOEEMDFDH-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621653   

TargetCarbonic anhydrase 2(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621653(CHEMBL5396279)
Affinity DataKi:  3.70nMAssay Description:Inhibition of recombinant human CA1I assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621653(CHEMBL5396279)
Affinity DataKi:  50nMAssay Description:Inhibition of recombinant human CA1 assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621653(CHEMBL5396279)
Affinity DataKi:  68nMAssay Description:Inhibition of recombinant human CA1X assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621653(CHEMBL5396279)
Affinity DataKi:  157nMAssay Description:Inhibition of recombinant human CA XII (30 to 291 residues) expressed in escherichia coli BL21 assessed as inhibition constant preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed