BDBM50621657 CHEMBL5418987

SMILES NS(=O)(=O)c1ccc(s1)-c1ccc(cn1)-c1ccnc2ccccc12

InChI Key InChIKey=MGBZVKFQSSXFAS-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621657   

TargetCarbonic anhydrase 2(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621657(CHEMBL5418987)
Affinity DataKi:  2.10nMAssay Description:Inhibition of recombinant human CA1I assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 12(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621657(CHEMBL5418987)
Affinity DataKi:  51nMAssay Description:Inhibition of recombinant human CA XII (30 to 291 residues) expressed in escherichia coli BL21 assessed as inhibition constant preincubated for 15 mi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 9(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621657(CHEMBL5418987)
Affinity DataKi:  61nMAssay Description:Inhibition of recombinant human CA1X assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assa...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCarbonic anhydrase 1(Human)
Latvian Institute of Organic Synthesis

Curated by ChEMBL
LigandPNGBDBM50621657(CHEMBL5418987)
Affinity DataKi:  73nMAssay Description:Inhibition of recombinant human CA1 assessed as inhibition constant preincubated for 15 mins by phenol red dye based stopped-flow CO2 hydration assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed