BDBM50621795 CHEMBL5438365

SMILES CNC(=O)Oc1cc(F)c2nc(-c3ccc4ccccc4c3)n(-c3ccnc(N[C@H]4CCCN(C4)C(=O)C4CC4)n3)c2c1

InChI Key InChIKey=CWLAIOPWFOOJHQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621795   

TargetMitogen-activated protein kinase 10(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621795(CHEMBL5438365)
Affinity DataIC50: 21nMAssay Description:Inhibition of JNK3 (unknown origin) using ATF2 as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 9(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621795(CHEMBL5438365)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of JNK2 (unknown origin) using ATF2 as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMitogen-activated protein kinase 8(Human)
Hanyang University

Curated by ChEMBL
LigandPNGBDBM50621795(CHEMBL5438365)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1 (unknown origin) using ATF2 as substrate incubated for 40 mins in presence of [gamma33P]ATP by scintillation counting analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed