BDBM50621801 CHEMBL5437398

SMILES C#CCNc1cc(C)cc2c(=O)cc(-c3ccc(OCCOCCN(Cc4ccc(C5(C(F)(F)F)N=N5)cc4)Cc4ccc(C5(C(F)(F)F)N=N5)cc4)cc3)oc12

InChI Key InChIKey=RVRVCSIZOXOSNT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621801   

TargetATP-dependent translocase ABCB1(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50621801BDBM50621801(CHEMBL5437398)
Affinity DataIC50: 312nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated PTX resistance by mea...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed