BDBM50621806 CHEMBL214738

SMILES Oc1cc(O)c2c(c1)oc(cc2=O)-c1ccc(OCCOCCOCCOCCOc2ccc(cc2)-c2cc(=O)c3c(O)cc(O)cc3o2)cc1

InChI Key InChIKey=VEVFLFVBUYKEOX-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621806   

TargetATP-dependent translocase ABCB1(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50621806(CHEMBL214738)
Affinity DataEC50:  900nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated paclitaxel resistance...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed