BDBM50621807 CHEMBL538668

SMILES O=c1cc(oc2ccccc12)-c1ccc(OCCOCCOCCOCCOc2ccc(cc2)-c2cc(=O)c3ccccc3o2)cc1

InChI Key InChIKey=MSCZOMOCPAFABK-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621807   

TargetATP-dependent translocase ABCB1(Human)
The Hong Kong Polytechnic University

Curated by ChEMBL
LigandPNGBDBM50621807(CHEMBL538668)
Affinity DataEC50:  360nMAssay Description:Negative allosteric modulator activity at P-gp in human LCC6MDR cells overexpressing P-gp assessed as reversal of P-gp mediated paclitaxel resistance...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed