BDBM50621832 CHEMBL5397495

SMILES Nc1nc(Nc2ccc(C#N)c(Cl)c2)nn1S(=O)(=O)c1cccc2cc(\C=C\C#N)ccc12

InChI Key InChIKey=RXXGEBPXQBMTIJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50621832   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621832(CHEMBL5397495)
Affinity DataIC50: 350nMAssay Description:Inhibition of HIV1 Reverse transcriptase incubated for 30 mins by fluorescence based analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetCytochrome P450 2C9(Human)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621832(CHEMBL5397495)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using diclofenac and sulfaphenazole as substrate preincubated for 5 mins followed by NADPH addition an...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Collaborations Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50621832(CHEMBL5397495)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of hERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed