BDBM50621838 CHEMBL5410873

SMILES [H][C@@]1(Cn2nncc2CNC1=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1c[nH]cn1)NC(C)=O

InChI Key InChIKey=KSNMTKCFCCBKIQ-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50621838   

TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataIC50: 9.60nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC1R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataEC50:  136nMAssay Description:Agonist activity at human MC1R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 5(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [I125] NDP-alpha-MSH from human MC5R stably overexpressing in HEK293 cells in presence of [I125] labeled NDP-alpha-MSH treated for 40...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetMelanocortin receptor 3(Human)
The University of Arizona

Curated by ChEMBL
LigandPNGBDBM50621838(CHEMBL5410873)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human MC3R stably overexpressing in HEK293 cells assessed as intracellular acumulation of cAMP level incubated for 30 mins measur...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed