BDBM50621991 CHEMBL5411709

SMILES CC(C)C[C@H]1c2c(c3ccc(cc3[nH]2)OC)C[C@@H]4N1C(=O)[C@@H](NC4=O)Cc5ccccc5

InChI Key InChIKey=MPOWCEOMANJKJZ-UHFFFAOYSA-N

Data  1 EC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621991   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich

Curated by ChEMBL

LigandBDBM50621991(CHEMBL5411709)Copy SMILESCopy InChI

Affinity DataEC50:  617nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPDBSimilars

In Depth
Date in BDB:
12/16/2024
Entry Details
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