BDBM50621999 CHEMBL5422584

SMILES [H][C@@]12Cc3c([nH]c4cc(OCCN)ccc34)[C@H](CC(C)C)N1C(=O)[C@H](CCC(=O)OC(C)(C)C)NC2=O

InChI Key InChIKey=QBFHXUOKMJSRDB-UHFFFAOYSA-N

Data  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50621999   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Human)
Eth Zurich

Curated by ChEMBL

LigandBDBM50621999(CHEMBL5422584)Copy SMILESCopy InChI

Affinity DataEC50: >1.00E+5nMAssay Description:Inhibition of human ABCG2 expressed in dog MDCK-II cells mediated mitoxantrone efflux incubated for preincubated for 15 mins followed by mitoxantrone...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/16/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL