BDBM506221 (S)-6-(( (Ml-(difluoromethyl)cyclopropyl)- 1H-1,2,3-triazol- 4-yl)(2-methyl-1-oxo-1,2- dihydroisoquinolin-5- yl)methyl)amino)-4- (neopentylamino)quinoline- 3,8-dicarbonitrile::US11066414, Compound 871
SMILES Cn1ccc2c([C@H](Nc3cc(C#N)c4ncc(C#N)c(NCC(C)(C)C)c4c3)C3=CN(C4(C(F)F)CC4)NN3)cccc2c1=O
InChI Key InChIKey=RDIDZEOLUYHRTC-UHFFFAOYSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 506221
Affinity DataIC50: 1nMAssay Description:EGFR activity was measured using KinEASE (Cisbio), a time-resolved fluorescence resonance energy transfer (TR-FRET) immunoassay. In this assay, EGFR-...More data for this Ligand-Target Pair
