BDBM50622138 CHEMBL5409745

SMILES CN1CCN(CC(=O)Nc2sc3CCCCc3c2C(=O)NCc2ccccc2)CC1

InChI Key InChIKey=XOHCSNDGRJYTBQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622138   

TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50622138(CHEMBL5409745)
Affinity DataIC50: 1.20nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50622138(CHEMBL5409745)
Affinity DataIC50: 1.60nMAssay Description:Binding affinity to yeast GAL4 DNA-binding domain fused human RORgammaT measured after 24 hrs by cellular luciferase based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed