BDBM50622141 CHEMBL5433435

SMILES C[C@@H]1CCN([C@H](C)C1)C(=O)c1c(NC(=O)c2cccnc2)sc2CCCCc12

InChI Key InChIKey=PCTBZMHJFHFNAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622141   

TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50622141(CHEMBL5433435)
Affinity DataIC50: 0.230nMAssay Description:Inverse agonist activity at GST-tagged RORgammaT LBD (unknown origin) expressed in insect cells assessed as inhibition of biotinyl-NH-Ahx NSHQKVTLLQL...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed
TargetNuclear receptor ROR-gamma(Human)
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50622141(CHEMBL5433435)
Affinity DataIC50: 100nMAssay Description:Binding affinity to yeast GAL4 DNA-binding domain fused human RORgammaT measured after 24 hrs by cellular luciferase based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/16/2024
Entry Details
PubMed