BDBM50622210 CHEMBL5417494

SMILES CN(Cc1ccccc1C)c1ncnc2[nH]c(cc12)-c1ccc(CO)cc1

InChI Key InChIKey=YKNNKGNQGPFRTQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622210   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622210BDBM50622210(CHEMBL5417494 | US20250353857, Compound TIA02-072)
Affinity DataIC50: 0.700nMAssay Description:Inhibition of CSF1R (530 to 910 residues) (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622210BDBM50622210(CHEMBL5417494 | US20250353857, Compound TIA02-072)
Affinity DataIC50: 0.700nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622210BDBM50622210(CHEMBL5417494 | US20250353857, Compound TIA02-072)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed