BDBM50622221 CHEMBL5398778

SMILES CN(Cc1cccc(C)c1)c1ncnc2[nH]c(cc12)-c1ccccc1

InChI Key InChIKey=HTIDNHAPXRJLIE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50622221   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622221(CHEMBL5398778)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622221(CHEMBL5398778)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CSF1R (unknown origin) using EEEIYGEFE as substrate in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622221(CHEMBL5398778)
Affinity DataIC50: 4nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra based T...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622221(CHEMBL5398778)
Affinity DataIC50: 17nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 2500 uM of ATP by LANCE Ultra TR-FR...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622221(CHEMBL5398778)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed