BDBM50622224 CHEMBL5425883

SMILES COCCOCCOCCOc1ccc(cc1)-c1cc2c(ncnc2[nH]1)N(C)Cc1cccc(C)c1

InChI Key InChIKey=HDUIQNARVJYUGR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622224   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622224BDBM50622224(CHEMBL5425883 | US20250353857, Compound NOR-4-004)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622224BDBM50622224(CHEMBL5425883 | US20250353857, Compound NOR-4-004)
Affinity DataIC50: 0.400nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622224BDBM50622224(CHEMBL5425883 | US20250353857, Compound NOR-4-004)
Affinity DataIC50: 117nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed