BDBM50622232 CHEMBL5411617

SMILES CN(Cc1cccc(C)c1)c1ncnc2[nH]c(cc12)-c1ccc(cc1)S(N)(=O)=O

InChI Key InChIKey=HNJOCLQAHHIZPS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50622232   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622232(CHEMBL5411617)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622232(CHEMBL5411617)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra TR-FRET...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622232(CHEMBL5411617)
Affinity DataIC50: 3nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 2500 uM of ATP by LANCE Ultra TR-FR...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandPNGBDBM50622232(CHEMBL5411617)
Affinity DataIC50: 98nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed