BDBM50622233 CHEMBL5415647

SMILES COC(=O)c1cccc(c1)-c1cc2c(ncnc2[nH]1)N(C)Cc1cccc(C)c1

InChI Key InChIKey=DNXZAQUXAXYLAN-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50622233   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50622233BDBM50622233(CHEMBL5415647 | US20250353857, Compound FAB01-23)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50622233BDBM50622233(CHEMBL5415647 | US20250353857, Compound FAB01-23)
Affinity DataIC50: 6.40nMMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
3/11/2026
Entry Details US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50622233BDBM50622233(CHEMBL5415647 | US20250353857, Compound FAB01-23)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of CSF1R (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50622233BDBM50622233(CHEMBL5415647 | US20250353857, Compound FAB01-23)
Affinity DataIC50: 30nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 25 uM of ATP by LANCE Ultra TR-FRET...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (NTNU)

US Patent
LigandChemical structure of BindingDB Monomer ID 50622233BDBM50622233(CHEMBL5415647 | US20250353857, Compound FAB01-23)
Affinity DataIC50: 80nMAssay Description:Inhibition of CSF1R (unknown origin) using ultra ULight GT peptide as substrate incubated for 1 hr in presence of 2500 uM of ATP by LANCE Ultra TR-FR...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Norwegian University of Science and Technology (NTNU)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622233BDBM50622233(CHEMBL5415647 | US20250353857, Compound FAB01-23)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) in presence of ATP by Z-LYTE based FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed