BDBM50622677 CHEMBL5433058

SMILES COc1ccc2-c3onc(C(=O)Nc4c(C)n(C)n(-c5ccccc5F)c4=O)c3CCCc2c1

InChI Key InChIKey=XAGYXKQSLBBSDU-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50622677   

TargetE3 ubiquitin-protein ligase SMURF1(Human)
Novartis Institutes of Biomedical Research (NIBR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622677BDBM50622677(CHEMBL5433058)
Affinity DataIC50: 200nMAssay Description:Inhibition of SMURF1 (unknown origin) assessed as self-ubiquitination by TR-FRET/biochemical assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed