BDBM50622678 CHEMBL5421627

SMILES COc1ccc(-c2onc(C(=O)Nc3c(C)n(C)n(-c4ccccc4F)c3=O)c2C)c(C)c1

InChI Key InChIKey=PUEGOUZDMYDGCG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50622678   

TargetE3 ubiquitin-protein ligase SMURF1(Human)
Novartis Institutes of Biomedical Research (NIBR)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622678BDBM50622678(CHEMBL5421627)
Affinity DataIC50: 180nMAssay Description:Inhibition of SMURF1 (unknown origin) assessed as self-ubiquitination by TR-FRET/biochemical assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed