BDBM50622895 CHEMBL5396476

SMILES CC(=O)O[C@H]1[C@@H]2O[C@]2([C@H](C)[C@H]2CC(CO)=C(C)C(=O)O2)[C@@]2(C)CCC3C(C[C@@H](O)[C@@]4(O)CC=CC(=O)[C@]34C)[C@@]12O

InChI Key InChIKey=VNEYTLXAFWQLRK-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50622895   

TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622895BDBM50622895(CHEMBL5396476)
Affinity DataKd:  2.60E+3nMAssay Description:Binding affinity to GLUT1 (unknown origin) assessed as dissociation constant at 800 uM by MST assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622895BDBM50622895(CHEMBL5396476)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of GLUT1 in human MCF7 cells assessed as ATP production incubated for 24 hrs in presence of 0.1 mM glucoseMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetSolute carrier family 2, facilitated glucose transporter member 1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50622895BDBM50622895(CHEMBL5396476)
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of GLUT1 in human MCF7 cells assessed as ATP production incubated for 24 hrs in presence of 10 mM glucoseMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed