BDBM50622926 CHEMBL5435454

SMILES NC(=O)c1ncc(nc1Nc1ccc(cc1)C1CCN(C[C@H]2CCN(C2)c2ccc3C(=O)N(C4CCC(=O)NC4=O)C(=O)c3c2)CC1)N1CCCCC1

InChI Key InChIKey=XLWJWCMQMBVNSG-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622926   

TargetTyrosine-protein kinase BTK(Human)
Nurix Therapeutics

Curated by ChEMBL
LigandPNGBDBM50622926(CHEMBL5435454)
Affinity DataKd:  18nMAssay Description:Binding affinity to BTK C481S mutant (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein kinase BTK(Human)
Nurix Therapeutics

Curated by ChEMBL
LigandPNGBDBM50622926(CHEMBL5435454)
Affinity DataKd:  45nMAssay Description:Binding affinity to BTK (unknown origin) assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed