BDBM50622990 CHEMBL5414944

SMILES CNCCCOc1ccc(CNc2ccccc2Oc2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=GQINFGHGGLEKAL-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50622990   

TargetVoltage-dependent N-type calcium channel subunit alpha-1B(Human)
Monash University

Curated by ChEMBL

LigandBDBM50622990(CHEMBL5414944)Copy SMILESCopy InChI

Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of Cav2.2 in human SH-SY5Y cells assessed as inhibition of calcium influx measured for 300 secs in presence of Cav1 blocker, nifedipine by...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
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TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Monash University

Curated by ChEMBL

LigandBDBM50622990(CHEMBL5414944)Copy SMILESCopy InChI

Affinity DataIC50: 2.04E+5nMAssay Description:Inhibition of human recombinant Cav3.2 alpha1 subunit expressed in HEK293T cells assessed as inhibition of calcium influx measured for 300 secs by FL...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoSimilars

In Depth
Date in BDB:
12/17/2024
Entry Details
Copy BDB DOIPubMed
Copy reaction URL