BDBM50623119 CHEMBL3216659

SMILES Brc1ccc2C(C(=O)Nc2c1)=C1Nc2ccccc2C1=N/OCCN1CCNCC1

InChI Key InChIKey=HJVDQPRJANOXIX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50623119   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50623119(CHEMBL3216659)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of recombinant GST-tagged c-Src catalytic domain (unknown origin) using pEY (4:1) as substrate incubated for 120 mins in presence of 33P-l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50623119(CHEMBL3216659)
Affinity DataIC50: 28nMAssay Description:Inhibition of recombinant GST-tagged JAK2 catalytic domain (unknown origin) using pEY (4:1) as substrate incubated for 120 mins in presence of 33P-la...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50623119(CHEMBL3216659)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant GST-tagged TYK2 catalytic domain (unknown origin) using pEY (4:1) as substrate incubated for 120 mins in presence of 33P-la...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetTyrosine-protein kinase JAK1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50623119(CHEMBL3216659)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant GST-tagged JAK1 catalytic domain (unknown origin) using pEY (4:1) as substrate incubated for 120 mins in presence of 33P-la...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed