BDBM50623245 CHEMBL5413609

SMILES Cc1[nH]c(C(=O)Nc2ccccc2OC2CCNC2)c(Cl)c1Cl

InChI Key InChIKey=BKOBTPYUNSNQGN-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623245   

TargetHeat shock protein HSP 90-beta(Human)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623245BDBM50623245(CHEMBL5413609)
Affinity DataKd:  2.60E+4nMAssay Description:Binding affinity to N-terminal His6-tagged human HSP90beta (1 to 239 residues) expressed in Escherichia coli BL21(DE3) cells by fluorescence thermal ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/4/2026
Entry Details
PubMed
TargetDNA topoisomerase 2-alpha(Human)
University of Ljubljana

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50623245BDBM50623245(CHEMBL5413609)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human DNA topoisomerase 2 alpha assessed as relaxation of supercoiled plasmid pNO1 DNA incubated for 30 mins by fluorescence based anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed