BDBM50623919 CHEMBL5422317

SMILES [H][C@]1(Cc2ccccc2CN1)[C@H](O)CN1CC(C)(C)c2cc(ccc2C1=O)C(=O)N1CCC2(CC2)CC1

InChI Key InChIKey=BHVYMDWQWQIEBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50623919   

TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50623919(CHEMBL5422317)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of PRMT5 in human Z138 cells assessed as decrease in sDMA modification incubated for 2 days by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50623919(CHEMBL5422317)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of PRMT5/MEP50 (unknown origin) using histone H4 peptide as substrate preincubated for 30 mins followed by substrate addition and measured...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed